Peri-Prosthetic Infection Management

Peri-prosthetic infection (PPI) is a serious complication that occurs around an artificial joint implant, such as hip, knee, or shoulder replacements. It can develop soon after surgery (early infection) or years later (late infection), causing pain, swelling, redness, warmth, and reduced joint function. Prompt and effective management is crucial to preserve the implant, restore joint function, and prevent systemic complications. Modern approaches combine advanced diagnostics, targeted antibiotics, and precise surgical techniques.

Causes of Peri-Prosthetic Infection
  • Bacterial contamination during surgery.
  • Spread of infection from another site in the body.
  • Delayed infections due to low-virulence organisms.
  • Compromised immunity or underlying health conditions (e.g., diabetes).
Diagnosis
  • Clinical Evaluation: Pain, swelling, redness, or warmth around the joint.
  • Laboratory Tests: Blood tests including ESR, CRP, and white blood cell count.
  • Joint Aspiration: Fluid sample from the joint for culture and sensitivity.
  • Imaging: X-rays, MRI, or nuclear scans to detect infection or loosening of implants.